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Does Antibody Stabilize the Ligand Binding in GP120 of HIV-1 Envelope Protein? Evidence from MD Simulation

CD4-mimetic HIV-1 entry inhibitors are small sized molecules which imitate similar conformational flexibility, in gp120, to the CD4 receptor. However, the mechanism of the conformational flexibility instigated by these small sized inhibitors is little known. Likewise, the effect of the antibody on t...

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Detalles Bibliográficos
Autores principales:	Yadav, Shalini, Pandey, Vishnudatt, Kumar Tiwari, Rakesh, Ojha, Rajendra Prasad, Dubey, Kshatresh Dutta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796314/ https://www.ncbi.nlm.nih.gov/pubmed/33466381 http://dx.doi.org/10.3390/molecules26010239

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