Gene Therapy for Progressive Familial Intrahepatic Cholestasis: Current Progress and Future Prospects

Progressive Familial Intrahepatic Cholestasis (PFIC) are inherited severe liver disorders presenting early in life, with high serum bile salt and bilirubin levels. Six types have been reported, two of these are caused by deficiency of an ABC transporter; ABCB11 (bile salt export pump) in type 2; ABC...

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Detalles Bibliográficos
Autores principales: Bosma, Piter J., Wits, Marius, Oude-Elferink, Ronald P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796371/
https://www.ncbi.nlm.nih.gov/pubmed/33383947
http://dx.doi.org/10.3390/ijms22010273

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