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Ascorbic acid can promote the generation and expansion of neuroepithelial-like stem cells derived from hiPS/ES cells under chemically defined conditions through promoting collagen synthesis

INTRODUCTION: Spinal cord injury (SCI) is a neurological, medically incurable disorder. Human pluripotent stem cells (hPSCs) have the potential to generate neural stem/progenitor cells (NS/PCs), which hold promise in the treatment of SCI by transplantation. In our study, we aimed to establish a chem...

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Detalles Bibliográficos
Autores principales: Bai, Rui, Chang, Yun, Saleem, Amina, Wu, Fujian, Tian, Lei, Zhang, Siyao, Li, Ya’nan, Ma, Shuhong, Dong, Tao, Guo, Tianwei, Jiang, Youxu, You, Yi, Lu, Wen-Jing, Jiang, Hong Feng, Lan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796386/
https://www.ncbi.nlm.nih.gov/pubmed/33422132
http://dx.doi.org/10.1186/s13287-020-02115-6