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Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

The presence of stereogenic elements is a common feature in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent issue in drug design. In this context, the study of the chiral molecular recognition mechanism fundamentally supports the understanding and optimization of c...

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Detalles Bibliográficos
Autores principales: Franzini, Roberta, Pierini, Marco, Mazzanti, Andrea, Iazzetti, Antonia, Ciogli, Alessia, Villani, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796420/
https://www.ncbi.nlm.nih.gov/pubmed/33375681
http://dx.doi.org/10.3390/ijms22010144