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Tryptophan and Kynurenine Enhances the Stemness and Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro and In Vivo

Aging tissues present a progressive decline in homeostasis and regenerative capacities, which has been associated with degenerative changes in tissue-specific stem cells and stem cell niches. We hypothesized that amino acids could regulate the stem cell phenotype and differentiation ability of human...

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Detalles Bibliográficos
Autores principales:	Pham, Hai Thanh, Ono, Mitsuaki, Hara, Emilio Satoshi, Nguyen, Ha Thi Thu, Dang, Anh Tuan, Do, Hang Thuy, Komori, Taishi, Tosa, Ikue, Hazehara-Kunitomo, Yuri, Yoshioka, Yuya, Oida, Yasutaka, Akiyama, Kentaro, Kuboki, Takuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796421/ https://www.ncbi.nlm.nih.gov/pubmed/33406724 http://dx.doi.org/10.3390/ma14010208

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