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Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8

BACKGROUND: Microglia are highly motile phagocytic cells in the healthy brain with surveillance and clearance functions. Although microglia have been shown to engulf cellular debris following brain insult, less is known about their phagocytic function in the absence of injury. Propofol can inhibit m...

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Detalles Bibliográficos
Autores principales: Cai, Xiaoying, Li, Ying, Zheng, Xiaoyang, Hu, Rong, Li, Yingyuan, Xiao, Liangcan, Wang, Zhongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796553/
https://www.ncbi.nlm.nih.gov/pubmed/33422097
http://dx.doi.org/10.1186/s12974-020-02061-3