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Connecting the conformational behavior of cyclic octadepsipeptides with their ionophoric property and membrane permeability
Cyclic octadepsipeptides such as PF1022A and its synthetic derivative emodepside exhibit anthelmintic activity with the latter sold as a commercial drug treatment against gastrointestinal nematodes for animal health use. The structure-permeability relationship of these cyclic depsipeptides that coul...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796559/ https://www.ncbi.nlm.nih.gov/pubmed/32902550 http://dx.doi.org/10.1039/d0ob01447h |