Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

MOTIVATION: Drug-induced liver injury (DILI) is one of the primary problems in drug development. Early prediction of DILI can bring a significant reduction in the cost of clinical trials. In this work we examined whether occurrence of DILI can be predicted using gene expression profile in cancer cel...

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Detalles Bibliográficos
Autores principales: Lesiński, Wojciech, Mnich, Krzysztof, Golińska, Agnieszka Kitlas, Rudnicki, Witold R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796564/
https://www.ncbi.nlm.nih.gov/pubmed/33422118
http://dx.doi.org/10.1186/s13062-020-00286-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796564/
https://www.ncbi.nlm.nih.gov/pubmed/33422118
http://dx.doi.org/10.1186/s13062-020-00286-z

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