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Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

MOTIVATION: Drug-induced liver injury (DILI) is one of the primary problems in drug development. Early prediction of DILI can bring a significant reduction in the cost of clinical trials. In this work we examined whether occurrence of DILI can be predicted using gene expression profile in cancer cel...

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Detalles Bibliográficos
Autores principales:	Lesiński, Wojciech, Mnich, Krzysztof, Golińska, Agnieszka Kitlas, Rudnicki, Witold R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796564/ https://www.ncbi.nlm.nih.gov/pubmed/33422118 http://dx.doi.org/10.1186/s13062-020-00286-z

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