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Development of an M cell targeted nanocomposite system for effective oral protein delivery: preparation, in vitro and in vivo characterization
BACKGROUND: There is a strong need for non-invasive and patient-friendly delivery systems of protein drugs for long-term therapy. However, oral delivery of protein drugs is a big challenge due to many barriers including instability in the gastrointestinal (GI) tract and low permeability. To overcome...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796596/ https://www.ncbi.nlm.nih.gov/pubmed/33422063 http://dx.doi.org/10.1186/s12951-020-00750-y |