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Required concentration index quantifies effective drug combinations against hepatitis C virus infection

Successful clinical drug development requires rational design of combination treatments based on preclinical data. Anti-hepatitis C virus (HCV) drugs exhibit significant diversity in antiviral effect. Dose-response assessments can be used to determine parameters profiling the diverse antiviral effec...

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Detalles Bibliográficos
Autores principales:	Kakizoe, Yusuke, Koizumi, Yoshiki, Ikoma, Yukino, Ohashi, Hirofumi, Wakita, Takaji, Iwami, Shingo, Watashi, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796629/ https://www.ncbi.nlm.nih.gov/pubmed/33422060 http://dx.doi.org/10.1186/s12976-020-00135-6

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