Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview

Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID‐19; i.e., chloroquine, lopinavir/ritonavir, ribavirin, tocilizumab, and...

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Autores principales: Rezaee, Haleh, Pourkarim, Fariba, Pourtaghi‐Anvarian, Samira, Entezari‐Maleki, Taher, Asvadi‐Kermani, Touraj, Nouri‐Vaskeh, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796804/
https://www.ncbi.nlm.nih.gov/pubmed/33421347
http://dx.doi.org/10.1002/prp2.705
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author Rezaee, Haleh
Pourkarim, Fariba
Pourtaghi‐Anvarian, Samira
Entezari‐Maleki, Taher
Asvadi‐Kermani, Touraj
Nouri‐Vaskeh, Masoud
author_facet Rezaee, Haleh
Pourkarim, Fariba
Pourtaghi‐Anvarian, Samira
Entezari‐Maleki, Taher
Asvadi‐Kermani, Touraj
Nouri‐Vaskeh, Masoud
author_sort Rezaee, Haleh
collection PubMed
description Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID‐19; i.e., chloroquine, lopinavir/ritonavir, ribavirin, tocilizumab, and remdesivir) and increase the risk of serious adverse reactions such as QT‐prolongation, retinopathy, increased risk of infection, and hepatotoxicity. This review focuses on summarizing DDIs for candidate medications used for COVID‐19 in order to minimize the adverse reactions.
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spelling pubmed-77968042021-01-15 Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview Rezaee, Haleh Pourkarim, Fariba Pourtaghi‐Anvarian, Samira Entezari‐Maleki, Taher Asvadi‐Kermani, Touraj Nouri‐Vaskeh, Masoud Pharmacol Res Perspect Reviews Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID‐19; i.e., chloroquine, lopinavir/ritonavir, ribavirin, tocilizumab, and remdesivir) and increase the risk of serious adverse reactions such as QT‐prolongation, retinopathy, increased risk of infection, and hepatotoxicity. This review focuses on summarizing DDIs for candidate medications used for COVID‐19 in order to minimize the adverse reactions. John Wiley and Sons Inc. 2021-01-09 /pmc/articles/PMC7796804/ /pubmed/33421347 http://dx.doi.org/10.1002/prp2.705 Text en © 2021 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Reviews
Rezaee, Haleh
Pourkarim, Fariba
Pourtaghi‐Anvarian, Samira
Entezari‐Maleki, Taher
Asvadi‐Kermani, Touraj
Nouri‐Vaskeh, Masoud
Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title_full Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title_fullStr Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title_full_unstemmed Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title_short Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
title_sort drug‐drug interactions with candidate medications used for covid‐19 treatment: an overview
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796804/
https://www.ncbi.nlm.nih.gov/pubmed/33421347
http://dx.doi.org/10.1002/prp2.705
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