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Deploying MMEJ using MENdel in precision gene editing applications for gene therapy and functional genomics
Gene-editing experiments commonly elicit the error-prone non-homologous end joining for DNA double-strand break (DSB) repair. Microhomology-mediated end joining (MMEJ) can generate more predictable outcomes for functional genomic and somatic therapeutic applications. We compared three DSB repair pre...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797032/ https://www.ncbi.nlm.nih.gov/pubmed/33305328 http://dx.doi.org/10.1093/nar/gkaa1156 |