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Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates

RECQ5 is one of five RecQ helicases found in humans and is thought to participate in homologous DNA recombination by acting as a negative regulator of the recombinase protein RAD51. Here, we use kinetic and single molecule imaging methods to monitor RECQ5 behavior on various nucleoprotein complexes....

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Detalles Bibliográficos
Autores principales:	Xue, Chaoyou, Molnarova, Lucia, Steinfeld, Justin B, Zhao, Weixing, Ma, Chujian, Spirek, Mario, Kaniecki, Kyle, Kwon, Youngho, Beláň, Ondrej, Krejci, Katerina, Boulton, Simon J, Sung, Patrick, Greene, Eric C, Krejci, Lumir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797033/ https://www.ncbi.nlm.nih.gov/pubmed/33332547 http://dx.doi.org/10.1093/nar/gkaa1184

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