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Reconstitution of mammalian mitochondrial translation system capable of correct initiation and long polypeptide synthesis from leaderless mRNA

Mammalian mitochondria have their own dedicated protein synthesis system, which produces 13 essential subunits of the oxidative phosphorylation complexes. We have reconstituted an in vitro translation system from mammalian mitochondria, utilizing purified recombinant mitochondrial translation factor...

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Detalles Bibliográficos
Autores principales: Lee, Muhoon, Matsunaga, Noriko, Akabane, Shiori, Yasuda, Ippei, Ueda, Takuya, Takeuchi-Tomita, Nono
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797035/
https://www.ncbi.nlm.nih.gov/pubmed/33300043
http://dx.doi.org/10.1093/nar/gkaa1165