Cargando…

APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A

Many APOBEC cytidine deaminase members are known to induce ‘off-target’ cytidine deaminations in 5′TC motifs in genomic DNA that contribute to cancer evolution. In this report, we characterized APOBEC1, which is a possible cancer related APOBEC since APOBEC1 mRNA is highly expressed in certain types...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Lai, Vizeacoumar, Frederick S, Vizeacoumar, Franco J, Chelico, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797036/ https://www.ncbi.nlm.nih.gov/pubmed/33330905 http://dx.doi.org/10.1093/nar/gkaa1201

Ejemplares similares

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes
por: Poulos, Rebecca C., et al.
Publicado: (2017)

Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines
por: Degtyareva, Natalya P., et al.
Publicado: (2013)

Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication
por: Cluett, Tricia J, et al.
Publicado: (2018)

Single-nucleotide polymorphism of the DNA cytosine deaminase APOBEC3H haplotype I leads to enzyme destabilization and correlates with lung cancer
por: Hix, Mark A, et al.
Publicado: (2020)

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity
por: Horn, Axel V., et al.
Publicado: (2014)

Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity
por: Bader, Samuel B, et al.
Publicado: (2021)

Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae
por: Prasai, Kanchanjunga, et al.
Publicado: (2017)

Highly organized DnaA–oriC complexes recruit the single-stranded DNA for replication initiation
por: Ozaki, Shogo, et al.
Publicado: (2012)

SV40 T antigen interactions with ssDNA and replication protein A: a regulatory role of T antigen monomers in lagging strand DNA replication
por: Onwubiko, Nichodemus O, et al.
Publicado: (2020)

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication
por: Obi, Ikenna, et al.
Publicado: (2020)

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis
por: Pilzecker, Bas, et al.
Publicado: (2016)

The DNA replication initiation protein DnaD recognises a specific strand of the Bacillus subtilis chromosome origin
por: Winterhalter, Charles, et al.
Publicado: (2023)

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
por: Bauerschmidt, Christina, et al.
Publicado: (2010)

p21 promotes error-free replication-coupled DNA double-strand break repair
por: Mauro, Maurizio, et al.
Publicado: (2012)

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
por: Yang, Yeran, et al.
Publicado: (2015)

Replicative DNA polymerases promote active displacement of SSB proteins during lagging strand synthesis
por: Cerrón, Fernando, et al.
Publicado: (2019)

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
por: Groth, Petra, et al.
Publicado: (2012)

Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage
por: Suspène, Rodolphe, et al.
Publicado: (2017)

Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes
por: Sparks, Melanie A, et al.
Publicado: (2019)

Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells
por: Kaushik Tiwari, Meetu, et al.
Publicado: (2016)

Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication
por: Allen, Jennifer M., et al.
Publicado: (2011)

Single-stranded DNA recruitment mechanism in replication origin unwinding by DnaA initiator protein and HU, an evolutionary ubiquitous nucleoid protein
por: Yoshida, Ryusei, et al.
Publicado: (2023)

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase
por: Kang, Yujin, et al.
Publicado: (2023)

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
por: Rouillon, Clément, et al.
Publicado: (2023)

Bacillus subtilis DNA polymerases, PolC and DnaE, are required for both leading and lagging strand synthesis in SPP1 origin-dependent DNA replication
por: Seco, Elena M., et al.
Publicado: (2017)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
por: Al-Minawi, Ali Z., et al.
Publicado: (2009)

Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability
por: Krawczyk, Claudia, et al.
Publicado: (2014)

Role for DNA double strand end-resection activity of RecBCD in control of aberrant chromosomal replication initiation in Escherichia coli
por: Goswami, Sayantan, et al.
Publicado: (2022)

Competition for DNA binding between the genome protector replication protein A and the genome modifying APOBEC3 single-stranded DNA deaminases
por: Wong, Lai, et al.
Publicado: (2022)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Flanking strand separation activity of RecA nucleoprotein filaments in DNA strand exchange reactions
por: Yu, Fangzhi, et al.
Publicado: (2023)

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks
por: Bolderson, Emma, et al.
Publicado: (2014)

Din7 and Mhr1 expression levels regulate double-strand-break–induced replication and recombination of mtDNA at ori5 in yeast
por: Ling, Feng, et al.
Publicado: (2013)

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis
por: Rannou, Olivier, et al.
Publicado: (2013)

Dna2 initiates resection at clean DNA double-strand breaks
por: Paudyal, Sharad C., et al.
Publicado: (2017)

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein
por: Yuan, Ying, et al.
Publicado: (2015)

Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2011)

Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation
por: Kim, Jusik, et al.
Publicado: (2020)

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
por: Muñoz-Galván, Sandra, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3ccn5d5eleos3truok3qoc7jd9