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Validation of human microRNA target pathways enables evaluation of target prediction tools

MicroRNAs are regulators of gene expression. A wide-spread, yet not validated, assumption is that the targetome of miRNAs is non-randomly distributed across the transcriptome and that targets share functional pathways. We developed a computational and experimental strategy termed high-throughput miR...

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Detalles Bibliográficos
Autores principales:	Kern, Fabian, Krammes, Lena, Danz, Karin, Diener, Caroline, Kehl, Tim, Küchler, Oliver, Fehlmann, Tobias, Kahraman, Mustafa, Rheinheimer, Stefanie, Aparicio-Puerta, Ernesto, Wagner, Sylvia, Ludwig, Nicole, Backes, Christina, Lenhof, Hans-Peter, von Briesen, Hagen, Hart, Martin, Keller, Andreas, Meese, Eckart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797041/ https://www.ncbi.nlm.nih.gov/pubmed/33305319 http://dx.doi.org/10.1093/nar/gkaa1161

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