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e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks
Understanding the functional impact of cancer somatic mutations represents a critical knowledge gap for implementing precision oncology. It has been increasingly appreciated that the interaction profile mediated by a genomic mutation provides a fundamental link between genotype and phenotype. Howeve...
Autores principales: | Li, Yongsheng, Burgman, Brandon, Khatri, Ishaani S, Pentaparthi, Sairahul R, Su, Zhe, McGrail, Daniel J, Li, Yang, Wu, Erxi, Eckhardt, S Gail, Sahni, Nidhi, Yi, S Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797045/ https://www.ncbi.nlm.nih.gov/pubmed/33211847 http://dx.doi.org/10.1093/nar/gkaa1015 |
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