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The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promyelocytic leukemia

BACKGROUND: Although arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) are well-tolerated and effective treatments for Acute Promyelocytic Leukemia (APL), Differentiation Syndrome (DS) is a lethal side effect in some patients. The pathogenesis of DS is complex and not well understood; howeve...

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Autores principales:	Mohammadzadeh, Zahra, Omidkhoda, Azadeh, Chahardouli, Bahram, Hoseinzadeh, Ghazaleh, Moghaddam, Kamran Ali, Mousavi, Seyed Asadollah, Rostami, Shahrbano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797108/ https://www.ncbi.nlm.nih.gov/pubmed/33422029 http://dx.doi.org/10.1186/s12885-021-07783-y

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