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CDKN2A (p16(INK4A)) affects the anti-tumor effect of CDK inhibitor in somatotroph adenomas
The altered cell cycle is associated with aberrant growth factor signaling in somatotroph adenoma, which is the primary cause of acromegaly. The aim of the present study was to investigate the pathological role of the INK4 family and evaluate the effectiveness of CDK4 inhibitor, palbociclib, in soma...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797444/ https://www.ncbi.nlm.nih.gov/pubmed/33416096 http://dx.doi.org/10.3892/ijmm.2020.4807 |