Cargando…

Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis

The main protease (M(pro)) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important therapeutic target as it plays a major role in the processing and maturation of the viral polyprotein. GC376 is a pre-clinical dipeptide-based protease inhibitor that has been previously used f...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharun, Khan, Tiwari, Ruchi, Dhama, Kuldeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797473/
https://www.ncbi.nlm.nih.gov/pubmed/33456770
http://dx.doi.org/10.1016/j.amsu.2020.12.030