P-cresol and Indoxyl Sulfate Impair Osteogenic Differentiation by Triggering Mesenchymal Stem Cell Senescence

Chronic kidney disease (CKD) patients obtained high levels of uremic toxins progressively develop several complications including bone fractures. Protein-bound uremic toxins especially p-cresol and indoxyl sulfate are hardly eliminated due to their high molecular weight. Thus, the abnormality of bon...

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Detalles Bibliográficos
Autores principales: Kamprom, Witchayapon, Tawonsawatruk, Tulyapruek, Mas-Oodi, Sumana, Anansilp, Korrarit, Rattanasompattikul, Manoch, Supokawej, Aungkura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797544/
https://www.ncbi.nlm.nih.gov/pubmed/33437209
http://dx.doi.org/10.7150/ijms.48492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797544/
https://www.ncbi.nlm.nih.gov/pubmed/33437209
http://dx.doi.org/10.7150/ijms.48492

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