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Clemastine promotes recovery of neural function and suppresses neuronal apoptosis by restoring balance of pro-inflammatory mediators in an experimental model of intracerebral hemorrhage

Intracerebral hemorrhage (ICH) represents a common acute cerebrovascular event that imparts high rates of disability. The microglia-mediated inflammatory response is a critical factor in determining cerebral damage post-ICH. Clemastine (CLM) is a histamine receptor H1 (HRH1) antagonist that has been...

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Detalles Bibliográficos
Autores principales: Zhi, Cheng, Zeng, Shulian, Chen, Yuan, Liao, Degui, Lai, Miaoling, Wang, Zhaotao, Wang, Yezhong, Xiao, Shiyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797547/
https://www.ncbi.nlm.nih.gov/pubmed/33437198
http://dx.doi.org/10.7150/ijms.51150