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Clemastine promotes recovery of neural function and suppresses neuronal apoptosis by restoring balance of pro-inflammatory mediators in an experimental model of intracerebral hemorrhage
Intracerebral hemorrhage (ICH) represents a common acute cerebrovascular event that imparts high rates of disability. The microglia-mediated inflammatory response is a critical factor in determining cerebral damage post-ICH. Clemastine (CLM) is a histamine receptor H1 (HRH1) antagonist that has been...
Autores principales: | Zhi, Cheng, Zeng, Shulian, Chen, Yuan, Liao, Degui, Lai, Miaoling, Wang, Zhaotao, Wang, Yezhong, Xiao, Shiyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797547/ https://www.ncbi.nlm.nih.gov/pubmed/33437198 http://dx.doi.org/10.7150/ijms.51150 |
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