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Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells

Extracellular vesicles (EVs), including exosomes and microvesicles, derived from bone marrow stromal cells (BMSCs) have been demonstrated as key factors in the progression and drug resistance of multiple myeloma (MM). EV uptake involves a variety of mechanisms which largely depend on the vesicle ori...

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Detalles Bibliográficos
Autores principales: Tu, Chenggong, Du, Zhimin, Zhang, Hui, Feng, Yueyuan, Qi, Yujun, Zheng, Yongjiang, Liu, Jinbao, Wang, Jinheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797667/
https://www.ncbi.nlm.nih.gov/pubmed/33500730
http://dx.doi.org/10.7150/thno.47996