Cargando…
Multi-omics study of silicosis reveals the potential therapeutic targets PGD(2) and TXA(2)
Rationale: Silicosis is a severe occupational lung disease. Current treatments for silicosis have highly limited availability (i.e., lung transplantation) or, do not effectively prolong patient survival time (i.e., lung lavage). There is thus an urgent clinical need for effective drugs to retard the...
Autores principales: | Pang, Junling, Qi, Xianmei, Luo, Ya, Li, Xiaona, Shu, Ting, Li, Baicun, Song, Meiyue, Liu, Ying, Wei, Dong, Chen, Jingyu, Wang, Jing, Wang, Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797695/ https://www.ncbi.nlm.nih.gov/pubmed/33500731 http://dx.doi.org/10.7150/thno.47627 |
Ejemplares similares
-
Comparative Transcriptome Analyses Reveal a Transcriptional Landscape of Human Silicosis Lungs and Provide Potential Strategies for Silicosis Treatment
por: Pang, Junling, et al.
Publicado: (2021) -
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration
por: Wang, Mingyao, et al.
Publicado: (2022) -
PGD Synthase and PGD(2) in Immune Resposne
por: Joo, Myungsoo, et al.
Publicado: (2012) -
Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis
por: Song, Meiyue, et al.
Publicado: (2022) -
Prostaglandin D(2) (PGD(2)); PGD(2) receptor subtype DP1
Publicado: (2011)