Cargando…

Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes

BACKGROUND: Excessive activation of immune responses in coronavirus disease 2019 (COVID-19) is considered to be related to disease severity, complications, and mortality rate. The complement system is an important component of innate immunity and can stimulate inflammation, but its role in COVID-19...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Nooijer, Aline H, Grondman, Inge, Janssen, Nico A F, Netea, Mihai G, Willems, Loek, van de Veerdonk, Frank L, Giamarellos-Bourboulis, Evangelos J, Toonen, Erik J M, Joosten, Leo A B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797765/ https://www.ncbi.nlm.nih.gov/pubmed/33038254 http://dx.doi.org/10.1093/infdis/jiaa646

Ejemplares similares

Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity
por: de Nooijer, Aline H., et al.
Publicado: (2023)

THE ROLE OF OBESITY AND PLASMA ADIPOCYTOKINES IN IMMUNE DYSREGULATION IN SEPSIS PATIENTS
por: de Nooijer, Aline H., et al.
Publicado: (2023)

A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients
por: Kooistra, Emma J., et al.
Publicado: (2021)

Abnormal Thyroid Function Is Associated With Lymphopenia in Bacterial Sepsis and COVID-19
por: Grondman, Inge, et al.
Publicado: (2021)

Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19
por: de Nooijer, Aline H., et al.
Publicado: (2021)

Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
por: Kooistra, Emma J., et al.
Publicado: (2020)

Increased Plasma Heparanase Activity in COVID-19 Patients
por: Buijsers, Baranca, et al.
Publicado: (2020)

Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia
por: Giamarellos-Bourboulis, Evangelos J, et al.
Publicado: (2011)

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection
por: Netea, Mihai G., et al.
Publicado: (2020)

The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses
por: Kuijpers, Yunus, et al.
Publicado: (2022)

Analysis of inflammatory protein profiles in the circulation of COVID-19 patients identifies patients with severe disease phenotypes
por: Keur, Nick, et al.
Publicado: (2023)

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study
por: Dellaporta, Erminia, et al.
Publicado: (2019)

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa
por: Kanni, Theodora, et al.
Publicado: (2015)

Characterization of sepsis inflammatory endotypes using circulatory proteins in patients with severe infection: a prospective cohort study
por: Ricaño-Ponce, Isis, et al.
Publicado: (2022)

Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis*
por: Karakike, Eleni, et al.
Publicado: (2021)

Editorial Introduction to the Supplement “Diagnosis of Infectious Diseases by Detection of Microbial Pathogens: A Joint Session Between HemoSpec FrameWork 7 Consortium with COST Action BM1401 Raman4Clinics Working Group 2”
por: Giamarellos-Bourboulis, Evangelos J.
Publicado: (2018)

Efficacy of BCG Vaccination Against Respiratory Tract Infections in Older Adults During the Coronavirus Disease 2019 Pandemic
por: Moorlag, Simone J C F M, et al.
Publicado: (2022)

Pitfalls in complement analysis: A systematic literature review of assessing complement activation
por: Brandwijk, Ricardo J. M. G. E., et al.
Publicado: (2022)

An Exaggerated Monocyte-Derived Cytokine Response to Candida Hyphae in Patients With Recurrent Vulvovaginal Candidiasis
por: Rosati, Diletta, et al.
Publicado: (2020)

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases
por: ten Oever, Jaap, et al.
Publicado: (2014)

Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals
por: Mylona, Eleni E, et al.
Publicado: (2012)

Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis
por: Dimopoulos, George, et al.
Publicado: (2020)

Long-Lasting Transcriptional Changes in Circulating Monocytes of Acute Q Fever Patients
por: Raijmakers, Ruud Ph, et al.
Publicado: (2019)

Complex immune deregulation in severe COVID-19: More than a mechanism of pathogenesis
por: Giamarellos-Bourboulis, Evangelos J.
Publicado: (2021)

A randomized clinical trial of bermekimab treatment for clinical improvement of systemic sclerosis
por: Solomonidi, Nicky, et al.
Publicado: (2023)

The role of trained immunity in COVID-19: Lessons for the next pandemic
por: Netea, Mihai G., et al.
Publicado: (2023)

Modulation of inflammation by autophagy: Consequences for human disease
por: Netea-Maier, Romana T., et al.
Publicado: (2015)

Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control
por: Giamarellos-Bourboulis, Evangelos J., et al.
Publicado: (2023)

Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control
por: Giamarellos-Bourboulis, Evangelos J., et al.
Publicado: (2023)

Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19
por: Zoodsma, Martijn, et al.
Publicado: (2022)

Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19
por: van de Veerdonk, Frank L., et al.
Publicado: (2020)

Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019( )
por: Castanha, Priscila M S, et al.
Publicado: (2022)

A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis
por: D’Onofrio, Valentino, et al.
Publicado: (2022)

The complex pathogenesis of bacteremia: From antimicrobial clearance mechanisms to the genetic background of the host
por: Christaki, Eirini, et al.
Publicado: (2014)

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis
por: Karakike, Eleni, et al.
Publicado: (2019)

Antimicrobial Stewardship Using Biomarkers: Accumulating Evidence for the Critically Ill
por: Kyriazopoulou, Evdoxia, et al.
Publicado: (2022)

Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients
por: de Graaf, Dennis M., et al.
Publicado: (2022)

IL-1β Processing in Host Defense: Beyond the Inflammasomes
por: Netea, Mihai G., et al.
Publicado: (2010)

Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity
por: Teufel, Lisa U., et al.
Publicado: (2023)

T-cell Subsets and Antifungal Host Defenses
por: van de Veerdonk, Frank L., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qe7vas1cltlpg8f88gqnu9iva4