Nuclear Factor Erythroid 2 Related Factor 2 Activator JC-5411 Inhibits Atherosclerosis Through Suppression of Inflammation and Regulation of Lipid Metabolism

Phenethyl isothiocyanate is widely present in cruciferous vegetables with multiple biological effects. Here we reported the antiatherogenic effects and the underlying mechanisms of JC-5411 (Phenethyl isothiocyanate formulation) in vitro and in vivo. Luciferase reporter assay showed that JC-5411 incr...

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Detalles Bibliográficos
Autores principales: Jiang, Xinhai, Li, Yining, Wang, Weizhi, Han, Xiaowan, Han, Jiangxue, Chen, Mingzhu, Zhang, Jing, Wang, Chenyin, Li, Shunwang, Luo, Jinque, Wang, Xiao, Xu, Yang, Xu, Yanni, Cheng, Jingcai, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797784/
https://www.ncbi.nlm.nih.gov/pubmed/33442380
http://dx.doi.org/10.3389/fphar.2020.532568

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