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Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model

Two outbreaks of severe respiratory infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) caused global pandemics and highlighted the importance of preparedness for respiratory CoVs. Recently, a third highly patho...

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Autores principales: Zhang, Zhaoyong, Zhang, Lu, Zhu, Airu, Wang, Yanqun, Guan, Wenda, Zeng, Zhiqi, Sun, Jing, Li, Fang, Zhao, Jingxian, Yang, Zifeng, Zhao, Jincun, Zhong, Nanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797876/
https://www.ncbi.nlm.nih.gov/pubmed/33447433
http://dx.doi.org/10.21037/jtd-20-2084
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author Zhang, Zhaoyong
Zhang, Lu
Zhu, Airu
Wang, Yanqun
Guan, Wenda
Zeng, Zhiqi
Sun, Jing
Li, Fang
Zhao, Jingxian
Yang, Zifeng
Zhao, Jincun
Zhong, Nanshan
author_facet Zhang, Zhaoyong
Zhang, Lu
Zhu, Airu
Wang, Yanqun
Guan, Wenda
Zeng, Zhiqi
Sun, Jing
Li, Fang
Zhao, Jingxian
Yang, Zifeng
Zhao, Jincun
Zhong, Nanshan
author_sort Zhang, Zhaoyong
collection PubMed
description Two outbreaks of severe respiratory infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) caused global pandemics and highlighted the importance of preparedness for respiratory CoVs. Recently, a third highly pathogenic CoV, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in Wuhan, Hubei, China and posed a public health crisis worldwide. Here, we focus on the recent advances of the novel CoV, and discuss its genomic similarity with other CoVs, transmission, animal model and clinical treatment of coronavirus disease 2019 (COVID-19) induced by SARS-CoV-2, which help epidemic prevention and control, and guide treatment strategies.
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spelling pubmed-77978762021-01-13 Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model Zhang, Zhaoyong Zhang, Lu Zhu, Airu Wang, Yanqun Guan, Wenda Zeng, Zhiqi Sun, Jing Li, Fang Zhao, Jingxian Yang, Zifeng Zhao, Jincun Zhong, Nanshan J Thorac Dis Review Article Two outbreaks of severe respiratory infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) caused global pandemics and highlighted the importance of preparedness for respiratory CoVs. Recently, a third highly pathogenic CoV, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in Wuhan, Hubei, China and posed a public health crisis worldwide. Here, we focus on the recent advances of the novel CoV, and discuss its genomic similarity with other CoVs, transmission, animal model and clinical treatment of coronavirus disease 2019 (COVID-19) induced by SARS-CoV-2, which help epidemic prevention and control, and guide treatment strategies. AME Publishing Company 2020-12 /pmc/articles/PMC7797876/ /pubmed/33447433 http://dx.doi.org/10.21037/jtd-20-2084 Text en 2020 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article
Zhang, Zhaoyong
Zhang, Lu
Zhu, Airu
Wang, Yanqun
Guan, Wenda
Zeng, Zhiqi
Sun, Jing
Li, Fang
Zhao, Jingxian
Yang, Zifeng
Zhao, Jincun
Zhong, Nanshan
Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title_full Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title_fullStr Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title_full_unstemmed Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title_short Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model
title_sort narrative review of the novel coronavirus sars-cov-2: update on genomic characteristics, transmissions and animal model
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797876/
https://www.ncbi.nlm.nih.gov/pubmed/33447433
http://dx.doi.org/10.21037/jtd-20-2084
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