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Thermal modulation of epicardial Ca(2+) dynamics uncovers molecular mechanisms of Ca(2+) alternans

Ca(2+) alternans (Ca-Alts) are alternating beat-to-beat changes in the amplitude of Ca(2+) transients that frequently occur during tachycardia, ischemia, or hypothermia that can lead to sudden cardiac death. Ca-Alts appear to result from a variation in the amount of Ca(2+) released from the sarcopla...

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Detalles Bibliográficos
Autores principales: Millet, Jose, Aguilar-Sanchez, Yuriana, Kornyeyev, Dmytro, Bazmi, Maedeh, Fainstein, Diego, Copello, Julio A., Escobar, Ariel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797898/
https://www.ncbi.nlm.nih.gov/pubmed/33410862
http://dx.doi.org/10.1085/jgp.202012568

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