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PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses

Delayed-type hypersensitivity (DTH) responses underpin chronic inflammation. Using a model of oxazolone-induced dermatitis and a combination of transgenic mice, adoptive cell transfer, and selective agonists/antagonists against protease activated receptors, we show that that PAR-1 signaling on macro...

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Detalles Bibliográficos
Autores principales:	Wilkinson, Hannah, Leonard, Hugh, Chen, Daxin, Lawrence, Toby, Robson, Michael, Goossens, Pieter., McVey, John H., Dorling, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797913/ https://www.ncbi.nlm.nih.gov/pubmed/33458623 http://dx.doi.org/10.1016/j.isci.2020.101981

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