Cargando…

P4HA1 regulates human colorectal cancer cells through HIF1α-mediated Wnt signaling

Colorectal cancer (CRC) is the third most commonly diagnosed malignancy that is associated with high levels of mortality. CRCs are often associated with an aberrant wingless-type mouse mammary tumor virus integration site family (Wnt) signaling pathway known to be responsible for tumorigenesis and c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qiang, Yin, Yue, Zhao, Hongye, Shi, Yan, Zhang, Wei, Yang, Zhengpeng, Liu, Tingting, Huang, Yonghong, Yu, Zhanjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798045/ https://www.ncbi.nlm.nih.gov/pubmed/33552264 http://dx.doi.org/10.3892/ol.2020.12406

Ejemplares similares

HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer
por: Zhang, Wenjing, et al.
Publicado: (2015)

HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts
por: Chen, Dafu, et al.
Publicado: (2013)

DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer
por: Hou, Pingfu, et al.
Publicado: (2019)

Hypoxia is fine-tuned by Hif-1α and regulates mesendoderm differentiation through the Wnt/β-Catenin pathway
por: Shen, Xiaopeng, et al.
Publicado: (2022)

HIF-1α Directly Controls WNT7A Expression During Myogenesis
por: Cirillo, Federica, et al.
Publicado: (2020)

OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis
por: Liu, Yue, et al.
Publicado: (2022)

Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF-1α through reducing endogenous GSH and inhibiting HIF-1α
por: Song, Bing, et al.
Publicado: (2017)

P4HA1 is a new regulator of the HIF-1 pathway in breast cancer
por: Xu, Ren
Publicado: (2019)

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
por: Wang, Mengdong, et al.
Publicado: (2023)

RPS7 inhibits colorectal cancer growth via decreasing HIF-1α-mediated glycolysis
por: Zhang, Wen, et al.
Publicado: (2015)

Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts
por: Chen, Dafu, et al.
Publicado: (2012)

VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α
por: Yue, Yiming, et al.
Publicado: (2023)

Effects of siRNA-mediated HIF-1α gene silencing on angiogenesis in osteosarcoma
por: Zhang, Xu-dong, et al.
Publicado: (2017)

PRMT3 promotes tumorigenesis by methylating and stabilizing HIF1α in colorectal cancer
por: Zhang, Xin, et al.
Publicado: (2021)

Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer
por: Chen, Yi-Hong, et al.
Publicado: (2022)

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
por: Branco-Price, Cristina, et al.
Publicado: (2012)

HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells
por: Wu, Lihua, et al.
Publicado: (2015)

ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer
por: Dong, Shuohui, et al.
Publicado: (2022)

HIF-1α Affects the Neural Stem Cell Differentiation of Human Induced Pluripotent Stem Cells via MFN2-Mediated Wnt/β-Catenin Signaling
por: Cui, Peng, et al.
Publicado: (2021)

HIF-transcribed p53 chaperones HIF-1α
por: Madan, Esha, et al.
Publicado: (2019)

HIF-1α participates in secondary brain injury through regulating neuroinflammation
por: Xu, Xiaojian, et al.
Publicado: (2023)

Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation
por: Wang, Pengcheng, et al.
Publicado: (2022)

LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation
por: Zhang, Jingjing, et al.
Publicado: (2016)

Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression
por: Hayek, Inaya, et al.
Publicado: (2022)

HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma
por: Lai, Xiang-Me, et al.
Publicado: (2017)

Efficacy of puerarin in rats with focal cerebral ischemia through modulation of the SIRT1/HIF-1α/VEGF signaling pathway and its effect on synaptic plasticity
por: Liu, Xin, et al.
Publicado: (2023)

ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer
por: He, Feng, et al.
Publicado: (2021)

A Novel Function of Novobiocin: Disrupting the Interaction of HIF 1α and p300/CBP through Direct Binding to the HIF1α C-Terminal Activation Domain
por: Wu, Donglu, et al.
Publicado: (2013)

HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways
por: Miranda da Costa, Natacha Malu, et al.
Publicado: (2019)

Berberine Reverses Hypoxia-induced Chemoresistance in Breast Cancer through the Inhibition of AMPK- HIF-1α
por: Pan, Yue, et al.
Publicado: (2017)

The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
por: Zheng, Fang, et al.
Publicado: (2021)

Expression of HIF-1α and HIF-2α correlates to biological and clinical significance in papillary thyroid carcinoma
por: Liu, Yan-Mei, et al.
Publicado: (2016)

Sun and survival with Hif1α
por: Tuma, Rabiya S.
Publicado: (2005)

HIF-1α in cerebral ischemia
por: Dong, Peiliang, et al.
Publicado: (2022)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

Insulin-Containing Wound Dressing Promotes Diabetic Wound Healing Through Stabilizing HIF-1α
por: Yang, Peilang, et al.
Publicado: (2020)

Adiponectin Treatment Attenuates Cerebral Ischemia-Reperfusion Injury through HIF-1α-Mediated Antioxidation in Mice
por: Zhang, Chan, et al.
Publicado: (2021)

HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition
por: Geng, Hao, et al.
Publicado: (2021)

SHMT2 Promotes Gastric Cancer Development through Regulation of HIF1α/VEGF/STAT3 Signaling
por: Wang, Weida, et al.
Publicado: (2023)

NQO1 inhibits proteasome-mediated degradation of HIF-1α
por: Oh, Eun-Taex, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tp305v89scim2veaul2l76fk02