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Cyclin D1 G870A Polymorphism: Relation to the Risk of ALL Development, Prognosis Impact, and Methotrexate Cytotoxicity

BACKGROUND: Cyclin D1 (CCND1) regulates cell cycle progression during the late G1 and S phase and takes part in methotrexate metabolism. It was hypothesized that CCND1 gene polymorphism affects acute lymphoblastic leukemia (ALL) development, prognosis and may relate to methotrexate cytotoxicity. SUB...

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Detalles Bibliográficos
Autores principales:	El Menshawy, Nadia, El Marghany, Ahmed B, Sarhan, Mohamed M, Aladle, Doaa A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798150/ https://www.ncbi.nlm.nih.gov/pubmed/33112552 http://dx.doi.org/10.31557/APJCP.2020.21.10.2941

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