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Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
Currently, there is no strong evidence of the well-established biomarkers for immune checkpoint inhibitors (ICIs) in nasopharyngeal carcinoma (NPC). Here, we aimed to reveal the heterogeneity of tumour microenvironment (TME) through virtual microdissection of gene expression profiles. An immune-enri...
Autores principales: | Chen, Yu-Pei, Lv, Jia-Wei, Mao, Yan-Ping, Li, Xiao-Min, Li, Jun-Yan, Wang, Ya-Qin, Xu, Cheng, Li, Ying-Qin, He, Qing-Mei, Yang, Xiao-Jing, Lei, Yuan, Shen, Jia-Yi, Tang, Ling-Long, Chen, Lei, Zhou, Guan-Qun, Li, Wen-Fei, Du, Xiao-Jing, Guo, Rui, Liu, Xu, Zhang, Yuan, Zeng, Jing, Yun, Jing-Ping, Sun, Ying, Liu, Na, Ma, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798236/ https://www.ncbi.nlm.nih.gov/pubmed/33430876 http://dx.doi.org/10.1186/s12943-020-01292-5 |
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