COCONUT online: Collection of Open Natural Products database

Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are bioactive. This potential raised great interest in NP research around the world and in different application fields, therefore, over the years...

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Autores principales: Sorokina, Maria, Merseburger, Peter, Rajan, Kohulan, Yirik, Mehmet Aziz, Steinbeck, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798278/
https://www.ncbi.nlm.nih.gov/pubmed/33423696
http://dx.doi.org/10.1186/s13321-020-00478-9
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author Sorokina, Maria
Merseburger, Peter
Rajan, Kohulan
Yirik, Mehmet Aziz
Steinbeck, Christoph
author_facet Sorokina, Maria
Merseburger, Peter
Rajan, Kohulan
Yirik, Mehmet Aziz
Steinbeck, Christoph
author_sort Sorokina, Maria
collection PubMed
description Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are bioactive. This potential raised great interest in NP research around the world and in different application fields, therefore, over the years a multiplication of generalistic and thematic NP databases has been observed. However, there is, at this moment, no online resource regrouping all known NPs in just one place, which would greatly simplify NPs research and allow computational screening and other in silico applications. In this manuscript we present the online version of the COlleCtion of Open Natural prodUcTs (COCONUT): an aggregated dataset of elucidated and predicted NPs collected from open sources and a web interface to browse, search and easily and quickly download NPs. COCONUT web is freely available at https://coconut.naturalproducts.net.
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spelling pubmed-77982782021-01-12 COCONUT online: Collection of Open Natural Products database Sorokina, Maria Merseburger, Peter Rajan, Kohulan Yirik, Mehmet Aziz Steinbeck, Christoph J Cheminform Database Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are bioactive. This potential raised great interest in NP research around the world and in different application fields, therefore, over the years a multiplication of generalistic and thematic NP databases has been observed. However, there is, at this moment, no online resource regrouping all known NPs in just one place, which would greatly simplify NPs research and allow computational screening and other in silico applications. In this manuscript we present the online version of the COlleCtion of Open Natural prodUcTs (COCONUT): an aggregated dataset of elucidated and predicted NPs collected from open sources and a web interface to browse, search and easily and quickly download NPs. COCONUT web is freely available at https://coconut.naturalproducts.net. Springer International Publishing 2021-01-10 /pmc/articles/PMC7798278/ /pubmed/33423696 http://dx.doi.org/10.1186/s13321-020-00478-9 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Database
Sorokina, Maria
Merseburger, Peter
Rajan, Kohulan
Yirik, Mehmet Aziz
Steinbeck, Christoph
COCONUT online: Collection of Open Natural Products database
title COCONUT online: Collection of Open Natural Products database
title_full COCONUT online: Collection of Open Natural Products database
title_fullStr COCONUT online: Collection of Open Natural Products database
title_full_unstemmed COCONUT online: Collection of Open Natural Products database
title_short COCONUT online: Collection of Open Natural Products database
title_sort coconut online: collection of open natural products database
topic Database
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798278/
https://www.ncbi.nlm.nih.gov/pubmed/33423696
http://dx.doi.org/10.1186/s13321-020-00478-9
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