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miR-107 affects cartilage matrix degradation in the pathogenesis of knee osteoarthritis by regulating caspase-1

BACKGROUND: Knee osteoarthritis (KOA) seriously affects the quality of life of KOA patients. This study aimed to investigate whether miR-107 could regulate KOA through pyroptosis to affect collagen protein secreted by chondrocytes through IL-1β. METHODS: The proliferation of chondrocytes was detecte...

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Detalles Bibliográficos
Autores principales:	Qian, Jiatian, Fu, Peiliang, Li, Shiao, Li, Xiang, Chen, Yancheng, Lin, Zhenen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798341/ https://www.ncbi.nlm.nih.gov/pubmed/33430857 http://dx.doi.org/10.1186/s13018-020-02121-7

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