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Clinical Assessment and Validation of a Rapid and Sensitive SARS-CoV-2 Test Using Reverse Transcription Loop-Mediated Isothermal Amplification Without the Need for RNA Extraction

BACKGROUND: Amid the enduring pandemic, there is an urgent need for expanded access to rapid, sensitive, and inexpensive coronavirus disease 2019 (COVID-19) testing worldwide without specialized equipment. We developed a simple test that uses colorimetric reverse transcription loop-mediated isotherm...

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Detalles Bibliográficos
Autores principales: Anahtar, Melis N, McGrath, Graham E G, Rabe, Brian A, Tanner, Nathan A, White, Benjamin A, Lennerz, Jochen K M, Branda, John A, Cepko, Constance L, Rosenberg, Eric S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798487/
https://www.ncbi.nlm.nih.gov/pubmed/34853795
http://dx.doi.org/10.1093/ofid/ofaa631