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The effect of angiotensin-converting enzyme levels on COVID-19 susceptibility and severity: a Mendelian randomization study

BACKGROUND: There has been uncertainty about the safety or benefit of angiotensin-converting enzyme (ACE) inhibitors during the COVID-19 pandemic. We used Mendelian randomization using genetic determinants of serum-ACE levels to test whether decreased ACE levels increase susceptibility to SARS-CoV-2...

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Detalles Bibliográficos
Autores principales:	Butler-Laporte, Guillaume, Nakanishi, Tomoko, Mooser, Vincent, Renieri, Alessandra, Amitrano, Sara, Zhou, Sirui, Chen, Yiheng, Forgetta, Vincenzo, Richards, J Brent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Covid-19
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799043/ https://www.ncbi.nlm.nih.gov/pubmed/33349849 http://dx.doi.org/10.1093/ije/dyaa229

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