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Piperazine-substituted derivatives of favipiravir for Nipah virus inhibition: What do in silico studies unravel?

Favipiravir is found to show excellent in-vitro inhibition activity against Nipah virus. To explore the structure–property relationship of Favipiravir, in silico designing of a series of piperazine substituted Favipiravir derivatives are attempted and computational screening has been done to evaluat...

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Detalles Bibliográficos
Autores principales: Lipin, Raju, Dhanabalan, Anantha Krishnan, Gunasekaran, Krishnasamy, Solomon, Rajadurai Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799160/
https://www.ncbi.nlm.nih.gov/pubmed/33458565
http://dx.doi.org/10.1007/s42452-020-04051-9