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Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing
Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOW(TM) and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The sp...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799223/ https://www.ncbi.nlm.nih.gov/pubmed/33367619 http://dx.doi.org/10.1093/cid/ciaa1890 |
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| author | Pilarowski, Genay Marquez, Carina Rubio, Luis Peng, James Martinez, Jackie Black, Douglas Chamie, Gabriel Jones, Diane Jacobo, Jon Tulier-Laiwa, Valerie Rojas, Susana Rojas, Susy Cox, Chesa Nakamura, Robert Petersen, Maya DeRisi, Joseph Havlir, Diane V |
| author_facet | Pilarowski, Genay Marquez, Carina Rubio, Luis Peng, James Martinez, Jackie Black, Douglas Chamie, Gabriel Jones, Diane Jacobo, Jon Tulier-Laiwa, Valerie Rojas, Susana Rojas, Susy Cox, Chesa Nakamura, Robert Petersen, Maya DeRisi, Joseph Havlir, Diane V |
| author_sort | Pilarowski, Genay |
| collection | PubMed |
| description | Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOW(TM) and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action. |
| format | Online Article Text |
| id | pubmed-7799223 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77992232021-01-25 Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing Pilarowski, Genay Marquez, Carina Rubio, Luis Peng, James Martinez, Jackie Black, Douglas Chamie, Gabriel Jones, Diane Jacobo, Jon Tulier-Laiwa, Valerie Rojas, Susana Rojas, Susy Cox, Chesa Nakamura, Robert Petersen, Maya DeRisi, Joseph Havlir, Diane V Clin Infect Dis Online only Articles Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOW(TM) and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action. Oxford University Press 2020-12-26 /pmc/articles/PMC7799223/ /pubmed/33367619 http://dx.doi.org/10.1093/cid/ciaa1890 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Online only Articles Pilarowski, Genay Marquez, Carina Rubio, Luis Peng, James Martinez, Jackie Black, Douglas Chamie, Gabriel Jones, Diane Jacobo, Jon Tulier-Laiwa, Valerie Rojas, Susana Rojas, Susy Cox, Chesa Nakamura, Robert Petersen, Maya DeRisi, Joseph Havlir, Diane V Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title | Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title_full | Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title_fullStr | Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title_full_unstemmed | Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title_short | Field Performance and Public Health Response Using the BinaxNOW(TM) Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing |
| title_sort | field performance and public health response using the binaxnow(tm) rapid severe acute respiratory syndrome coronavirus 2 (sars-cov-2) antigen detection assay during community-based testing |
| topic | Online only Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799223/ https://www.ncbi.nlm.nih.gov/pubmed/33367619 http://dx.doi.org/10.1093/cid/ciaa1890 |
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