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Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection
There is a critical need for safe and effective drugs for COVID‐19. Only remdesivir has received authorization for COVID‐19 and has been shown to improve outcomes but not decrease mortality. However, the dose of remdesivir is limited by hepatic and kidney toxicity. ACE2 is the critical cell surface...
Autores principales: | Monteil, Vanessa, Dyczynski, Matheus, Lauschke, Volker M, Kwon, Hyesoo, Wirnsberger, Gerald, Youhanna, Sonia, Zhang, Haibo, Slutsky, Arthur S, Hurtado del Pozo, Carmen, Horn, Moritz, Montserrat, Nuria, Penninger, Josef M, Mirazimi, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799356/ https://www.ncbi.nlm.nih.gov/pubmed/33179852 http://dx.doi.org/10.15252/emmm.202013426 |
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