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Hippocampal low-frequency stimulation prevents seizure generation in a mouse model of mesial temporal lobe epilepsy

Mesial temporal lobe epilepsy (MTLE) is the most common form of focal, pharmacoresistant epilepsy in adults and is often associated with hippocampal sclerosis. Here, we established the efficacy of optogenetic and electrical low-frequency stimulation (LFS) in interfering with seizure generation in a...

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Detalles Bibliográficos
Autores principales: Paschen, Enya, Elgueta, Claudio, Heining, Katharina, Vieira, Diego M, Kleis, Piret, Orcinha, Catarina, Häussler, Ute, Bartos, Marlene, Egert, Ulrich, Janz, Philipp, Haas, Carola A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7800381/
https://www.ncbi.nlm.nih.gov/pubmed/33349333
http://dx.doi.org/10.7554/eLife.54518

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