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Pristimerin Protects Against OVX-Mediated Bone Loss by Attenuating Osteoclast Formation and Activity via Inhibition of RANKL-Mediated Activation of NF-κB and ERK Signaling Pathways
INTRODUCTION: Osteoporosis is an osteolytic bone condition characterized by decreased bone strength and increased bone fragility. It is the result of elevated formation or activity of bone-resorbing osteoclasts. Although current therapeutic agents are efficacious against osteoclast-mediated bone los...
Autores principales: | Li, Xuedong, Lin, Xixi, Wu, Zuoxing, Su, Yuangang, Liang, Jiamin, Chen, Runfeng, Yang, Xue, Hou, Lei, Zhao, Jinmin, Liu, Qian, Xu, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7800467/ https://www.ncbi.nlm.nih.gov/pubmed/33442237 http://dx.doi.org/10.2147/DDDT.S283694 |
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