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Mitochondrial heteroplasmy profiling in single human oocytes by next-generation sequencing

Mitochondrial DNA (mtDNA) plays a key role in the development of a competent oocyte. Mutations of the mitochondrial genome lead to an altered energetic metabolism with negative effects on oocyte developmental competence. In this study, mtDNA heteroplasmy at an intra-oocyte level and between the diff...

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Detalles Bibliográficos
Autores principales:	Ancora, Massimo, Orsini, Massimiliano, Colosimo, Alessia, Russo, Valentina, Marcacci, Maurilia, De Santo, Maria, D’Aurora, Marco, Stuppia, Liborio, Gatta, Valentina, Barboni, Barbara, Cammà, Cesare, Mattioli, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Mitogenome Announcement
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7800564/ https://www.ncbi.nlm.nih.gov/pubmed/33473893 http://dx.doi.org/10.1080/23802359.2017.1365634

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