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Effects of Remimazolam and Propofol on Ca(2+) Regulation by Ryanodine Receptor 1 with Malignant Hyperthermia Mutation

BACKGROUND: We investigated the potential safety of remimazolam and propofol in malignant hyperthermia- (HM-) susceptible patients using ryanodine receptor 1- (RYR1-) expressing human embryonic kidney- (HEK-) 293 cells. METHODS: We compared the enhanced responsiveness of HEK-293 cells expressing wil...

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Detalles Bibliográficos
Autores principales: Watanabe, Tomoyuki, Miyoshi, Hirotsugu, Noda, Yuko, Narasaki, Soshi, Morio, Atsushi, Toyota, Yukari, Kimura, Hiroshi, Mukaida, Keiko, Yasuda, Toshimichi, Tsutsumi, Yasuo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801102/
https://www.ncbi.nlm.nih.gov/pubmed/33490280
http://dx.doi.org/10.1155/2021/8845129

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