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The insulin-degrading enzyme as a link between insulin and neuropeptides metabolism

We have applied a recently developed HPLC-MS enzymatic assay to investigate the cryptic peptides generated by the action of the insulin-degrading enzyme (IDE) on some neuropeptides (NPs) involved in the development of tolerance and dependence to opioids. Particularly, the tested NPs are generated fr...

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Detalles Bibliográficos
Autores principales:	Wacławczyk, Dorota, Silberring, Jerzy, Grasso, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801110/ https://www.ncbi.nlm.nih.gov/pubmed/33401948 http://dx.doi.org/10.1080/14756366.2020.1850712

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