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Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles

Newly synthesised benzimidazole/benzotiazole derivatives bearing amidino, namely 3,4,5,6-tetrahydropyrimidin-1-ium chloride, substituents have been evaluated for their potential antitumor activity in vitro. Compounds and standard drugs (doxorubicin, staurosporine and vandetanib) were tested on three...

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Detalles Bibliográficos
Autores principales: Racané, Livio, Cindrić, Maja, Zlatar, Ivo, Kezele, Tatjana, Milić, Astrid, Brajša, Karmen, Hranjec, Marijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801115/
https://www.ncbi.nlm.nih.gov/pubmed/33404264
http://dx.doi.org/10.1080/14756366.2020.1850711