Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence

The Coronavirus disease-2019 (COVID-19) pandemic is an unprecedented health care crisis and has led to over 1.5 million deaths worldwide. The risk of severe COVID-19 and mortality is markedly raised in patients with cancer, prompting several collaborative groups to issue guidelines to mitigate the r...

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Autores principales: Singh, Suvir, Singh, Jagdeep, Paul, Davinder, Jain, Kunal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801183/
https://www.ncbi.nlm.nih.gov/pubmed/33558204
http://dx.doi.org/10.1016/j.clml.2021.01.004
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author Singh, Suvir
Singh, Jagdeep
Paul, Davinder
Jain, Kunal
author_facet Singh, Suvir
Singh, Jagdeep
Paul, Davinder
Jain, Kunal
author_sort Singh, Suvir
collection PubMed
description The Coronavirus disease-2019 (COVID-19) pandemic is an unprecedented health care crisis and has led to over 1.5 million deaths worldwide. The risk of severe COVID-19 and mortality is markedly raised in patients with cancer, prompting several collaborative groups to issue guidelines to mitigate the risk of infection by delaying or de-escalating immunosuppressive therapy. However, delayed therapy is often not feasible for patients requiring treatment for acute leukemia or stem cell transplantation. We provide a focused review of the recommendations and evidence for managing this high-risk group of patients while minimizing the risk of COVID-19 infection, and provide a small snapshot of treatment data from our center.
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spelling pubmed-78011832021-01-12 Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence Singh, Suvir Singh, Jagdeep Paul, Davinder Jain, Kunal Clin Lymphoma Myeloma Leuk Review The Coronavirus disease-2019 (COVID-19) pandemic is an unprecedented health care crisis and has led to over 1.5 million deaths worldwide. The risk of severe COVID-19 and mortality is markedly raised in patients with cancer, prompting several collaborative groups to issue guidelines to mitigate the risk of infection by delaying or de-escalating immunosuppressive therapy. However, delayed therapy is often not feasible for patients requiring treatment for acute leukemia or stem cell transplantation. We provide a focused review of the recommendations and evidence for managing this high-risk group of patients while minimizing the risk of COVID-19 infection, and provide a small snapshot of treatment data from our center. Elsevier Inc. 2021-05 2021-01-12 /pmc/articles/PMC7801183/ /pubmed/33558204 http://dx.doi.org/10.1016/j.clml.2021.01.004 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Singh, Suvir
Singh, Jagdeep
Paul, Davinder
Jain, Kunal
Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title_full Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title_fullStr Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title_full_unstemmed Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title_short Treatment of Acute Leukemia During COVID-19: Focused Review of Evidence
title_sort treatment of acute leukemia during covid-19: focused review of evidence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801183/
https://www.ncbi.nlm.nih.gov/pubmed/33558204
http://dx.doi.org/10.1016/j.clml.2021.01.004
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