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Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play

An ever-increasing ageing population has elevated Alzheimer’s disease to be one of the biggest challenges in modern medicine. Alzheimer’s disease is highly complex, and we are still no closer to understanding the causes, let alone an effective treatment. The lack of good experimental models and lack...

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Detalles Bibliográficos
Autores principales: Tan, Shawn Zheng Kai, Zhao, Robert Chunhua, Chakrabarti, Sasanka, Stambler, Ilia, Jin, Kunlin, Lim, Lee Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801283/
https://www.ncbi.nlm.nih.gov/pubmed/33532125
http://dx.doi.org/10.14336/AD.2020.0602
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author Tan, Shawn Zheng Kai
Zhao, Robert Chunhua
Chakrabarti, Sasanka
Stambler, Ilia
Jin, Kunlin
Lim, Lee Wei
author_facet Tan, Shawn Zheng Kai
Zhao, Robert Chunhua
Chakrabarti, Sasanka
Stambler, Ilia
Jin, Kunlin
Lim, Lee Wei
author_sort Tan, Shawn Zheng Kai
collection PubMed
description An ever-increasing ageing population has elevated Alzheimer’s disease to be one of the biggest challenges in modern medicine. Alzheimer’s disease is highly complex, and we are still no closer to understanding the causes, let alone an effective treatment. The lack of good experimental models and lack of critical understanding has led to high failure rates of clinical trials with high associated costs, as well as difficulties in implementing treatments. The multifaceted nature of this disease highlights the need for an interdisciplinary approach to address these concerns. In this essay, we suggest how collaborative work can be useful in addressing some of the above issues. We then propose that international organisations and publishers need to support interdisciplinary research by creating platforms, lobbying funders, and pushing for interdisciplinary publications. We further highlight some of the issues involved in implementing these suggestions and argue that willpower of the research community, together with a re-evaluation of evaluation metrics and incentive systems, are needed in order to foster interdisciplinary research. Overall, we emphasise the need for interdisciplinary research in Alzheimer’s disease and suggest that international societies should play a huge role in this endeavour.
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spelling pubmed-78012832021-02-01 Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play Tan, Shawn Zheng Kai Zhao, Robert Chunhua Chakrabarti, Sasanka Stambler, Ilia Jin, Kunlin Lim, Lee Wei Aging Dis Commentary An ever-increasing ageing population has elevated Alzheimer’s disease to be one of the biggest challenges in modern medicine. Alzheimer’s disease is highly complex, and we are still no closer to understanding the causes, let alone an effective treatment. The lack of good experimental models and lack of critical understanding has led to high failure rates of clinical trials with high associated costs, as well as difficulties in implementing treatments. The multifaceted nature of this disease highlights the need for an interdisciplinary approach to address these concerns. In this essay, we suggest how collaborative work can be useful in addressing some of the above issues. We then propose that international organisations and publishers need to support interdisciplinary research by creating platforms, lobbying funders, and pushing for interdisciplinary publications. We further highlight some of the issues involved in implementing these suggestions and argue that willpower of the research community, together with a re-evaluation of evaluation metrics and incentive systems, are needed in order to foster interdisciplinary research. Overall, we emphasise the need for interdisciplinary research in Alzheimer’s disease and suggest that international societies should play a huge role in this endeavour. JKL International LLC 2021-02-01 /pmc/articles/PMC7801283/ /pubmed/33532125 http://dx.doi.org/10.14336/AD.2020.0602 Text en copyright: © 2021 Tan et al. http://creativecommons.org/licenses/by/2.0/ this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Commentary
Tan, Shawn Zheng Kai
Zhao, Robert Chunhua
Chakrabarti, Sasanka
Stambler, Ilia
Jin, Kunlin
Lim, Lee Wei
Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title_full Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title_fullStr Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title_full_unstemmed Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title_short Interdisciplinary Research in Alzheimer’s Disease and the Roles International Societies Can Play
title_sort interdisciplinary research in alzheimer’s disease and the roles international societies can play
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801283/
https://www.ncbi.nlm.nih.gov/pubmed/33532125
http://dx.doi.org/10.14336/AD.2020.0602
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