Ultraviolet radiation drives mutations in a subset of mucosal melanomas

Although identified as the key environmental driver of common cutaneous melanoma, the role of ultraviolet radiation (UVR)-induced DNA damage in mucosal melanoma is poorly defined. We analyze 10 mucosal melanomas of conjunctival origin by whole genome sequencing and our data shows a predominance of U...

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Detalles Bibliográficos
Autores principales: Mundra, Piyushkumar A., Dhomen, Nathalie, Rodrigues, Manuel, Mikkelsen, Lauge Hjorth, Cassoux, Nathalie, Brooks, Kelly, Valpione, Sara, Reis-Filho, Jorge S., Heegaard, Steffen, Stern, Marc-Henri, Roman-Roman, Sergio, Marais, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801393/
https://www.ncbi.nlm.nih.gov/pubmed/33431815
http://dx.doi.org/10.1038/s41467-020-20432-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801393/
https://www.ncbi.nlm.nih.gov/pubmed/33431815
http://dx.doi.org/10.1038/s41467-020-20432-5

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